This is the most awesome start-up manager I have ever found. It helps you decide to do with each start-up item. It has a surprise interface too.
Windows XP/Vista/7 (32bit & 64bit)
What is Soluto Beta?
Soluto Beta allows you to understand your boot, discover which applications are slowing it down (and keep running later in the background, affecting your ongoing experience), and allows you to significantly improve it. While Soluto Beta focuses on the boot, it already researches for frustrations and helps map the PC Genome, allowing you to share your wisdom with others.
Soluto is rapidly gaining popularity since it's inception last May and now that new version updates are being introduced.
Here is another article on it separate from the newsletter where I discovered it.